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Paraquat is taken up into dopaminergic terminals by the dopamine transport and organic cation transporter 3 (Rappold et al., 2011), and causes cellular toxicity by oxidative stress through the cellular redox cycling generating superoxide radical by the oxidation of NADPH, which in turn impairs the restauration of GSH levels and thus the activity of several antioxidant systems (Berry et al., 2002

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Advancing biosensors with machine learning

It is characterized by reduced kidney function, indicated by a glomerular filtration rate (GFR) of less than 60 mL/min per 1.73 m 2 , or markers of kidney damage, such as albuminuria (albumin: creatinine ratio 30 mg/g), or both, that persist for a minimum of 3 months, irrespective of the underlying cause (2, 4, 7, 9)

For each z-score increase in Glutathione, participants took 817 additional steps/day (95% CI: -89.2, 1723.4

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