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6,7 Avoiding future exposure to drugs of the same pharmacologic class as the drug that triggered SJS/TEN is suggested because there can be cross-reactivity (eg, antiepileptics with aromatic structures such as phenytoin, carbamazepine, and phenobarbital or beta-lactam antibiotics)

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Uric acid stimulates proliferative pathways in vascular smooth muscle cells through the activation of p38 MAPK, p44/42 MAPK and PDGFR

Made from three amino acids: glutamine, cysteine, and glycine, its main function is to neutralize free radicals

Mitochondrial permeability transition pore opening during myocardial reperfusiona target for cardioprotection