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Taking together all the studies discussed in this review, it seems reasonable to conclude that NRF2 is part of the sleep biochemical regulatory network

Paietta E, Racevskis J, Stanley ER, Andreeff M , Papenhausen P, Wiernik PH

Full text: Jain, S

Given that vitamin B12 deficiency can cause neurologic deficits, a dementia caused by B12 deficiency is thought to be reversible

Because the decline in the function of the pathway during aging has been linked to degenerative diseases, these drugs represent exciting candidates for prevention of cognitive decline and other degenerative diseases of aging