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MOTS-c has a half-life of 46 hours and works best when administered during metabolic windows where AMPK activation is already primedfasted states, pre-training, or during caloric deficit periods

These findings have not been replicated in human trials

This is due to a few physiological differences between the sexes

Metabolism does not appear to be altered by chronic exposure, thus dose escalation appears to arise from pharmacodynamic rather than pharmacokinetic tolerance [24]

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Podobnie jak w przypadku innych substancji wpywajcych na organizm na poziomie komrkowym, warto wiedzie, jakie reakcje mog si pojawi, aby mc je odpowiednio monitorowa i reagowa na ewentualne problemy