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NAM relieves mitochondrial ROS by enhancing the expression or activity mitochondrial antioxidant enzymes To determine the effect of NAM on the cellular oxidative stress level, MC3T3-E1 cells were stained with a fluorogenic probe, CellROX TM , which measures the ROS level in the cytosol, and MitoSOX TM , which measures superoxide production in mitochondria

A novel variant of human superoxide dismutase 1 harboring amyotrophic lateral sclerosis-associated and experimental mutations in metal-binding residues and free cysteines lacks toxicity in vivo

LiZDaiHHuangXFengJDengJWangZet alArtesunate synergizes with sorafenib to induce ferroptosis in hepatocellular carcinoma

This challenge can be overcome via intratracheal (i.t.) administration of macrophage cell membrane-based nanovesicles

doi: 10.1016/S0960-9822(02)00809-6 229 HiguchiFUchidaSYamagataHAbe-HiguchiNHobaraTHaraKet al