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Post-stroke efferocytosis Efferocytosis as a brain homeostatic process Efferocytosis is a brain homeostatic mechanism responsible for the removal of ACs that have accumulated within the brain tissue due to diverse pathological conditions [11]

(5) Protecting mitochondrial function

During cellular respiration, electrons are transferred through a series of complexes in the inner mitochondrial membrane to ultimately reduce oxygen to water

CAT assay CAT activity was determined using supernatants from infected and non-infected cells

Future studies should include female animals to fully elucidate whether the beneficial effects of irisin are consistent across both sexes and to better understand the underlying mechanisms involved

Jurcu MC, Andronie-Cioara FL, Jurcu A et al (2022) The link between oxidative stress, mitochondrial dysfunction and neuroinflammation in the pathophysiology of Alzheimers disease: therapeutic implications and future perspectives