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Description

The LRRK2-RAB axis in regulation of vesicle trafficking and -synuclein propagation

PLoS One 15, e0244680

This enhances the diversity of DAMP release, overcomes tumor-intrinsic resistance, promotes broader antigen presentation and epitope spreading, and amplifies synergy with immune adjuvants or checkpoint blockade, ultimately leading to more robust and durable antitumor immunity