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It is known that some chemicals which alter the genes involved in the HPT axis homeostasis may be associated with an increased incidence of thyroid dysfunction, such as hypothyroidism, hyperthyroidism and cancer (6972)

Ahmed AM, Lopez I, Perese F, Vasquez R, Hynan LS, Chong B, et al

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Levodopa substitution is still the most effective approach to treat PD motor symptoms, but standard oral drug delivery is associated with plasma level oscillations that give rise to the development of motor fluctuations and dyskinesias

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