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Description

Research has demonstrated involvement of the NO system, growth factor modulation (including VEGF, EGF), and FAK-paxillin signaling pathways

Exp Neurol

(2019) 87:e00570-19

and DMSO-induced histamine release by mast cells

The catalytic glutamate residue E 115 accepts a proton from the -glutamyl group of the substrate, initiating a nucleophilic attack by the amine on the amide carbon atom