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Sublingual sprays provide a completely needle-free alternative

In a typical encapsulation experiment, PLGA nanoparticles exhibited a hydrodynamic diameter of 170 30 nm (z-average, PDI = 0.162) as measured using dynamic light scattering with anionic effective surface charge (20.5 5.3 mV) due to the terminal carboxylate groups on the PLGA polymers

On the other hand, in hyperglycemic rats induced with STZ-NA, the extract reduced postprandial hyperglycemia by inhibiting the glucose peak at 30 min and promoting the return of glucose to basal levels at 120 min

PLL Therapeutics obtains authorization to start phase I/II trial in Australia for patients with amyotrophic lateral sclerosis (ALS)

YX and QZ conducted data analyses and blood measurements

Nature (London) 580 (7803), 329338 (2020) P