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Targeting histone deacetylases: emerging applications beyond cancer

By focusing on a subset of aged degus that show AD-like behavioral deficits and correlative neuropathology, we establish outbred degus as a natural model of sporadic AD and demonstrate the potential importance of wild-type outbred genetic backgrounds for AD pathogenesis. This study was motivated by the need to settle earlier debates of whether degus can be a useful natural model of AD

More research is required in humans although there is some evidence supporting the use of acetyl-L-carnitine to treat mild cognitive impairment and mild Alzheimers disease

Accelerated aging phenotype in mice with conditional deficiency for mitochondrial superoxide dismutase in the connective tissue

Leaf chlorophyll fluorescence and reflectance of oakleaf lettuce exposed to metal and metal(oid) oxide nanoparticles

A novel promoter element containing multiple overlapping xenobiotic and hypoxia response elements mediates induction of cytochrome P4502S1 by both dioxin and hypoxia