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Notably, NADPH depletion in SLC7A11 high cancer cells results in disulfide stress accumulation and cytoskeleton remodeling, eliciting disulfidptosis under glucose starvation 28

In deeply anesthetized rats, laparatomized before sacrifice, we assessed the gross lesions in the gastrointestinal tract and in the stomach (sum of the longest diameters, mm) (Gojkovic et al., 2020

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The combination of methylcobalamin and folinic acid induced increases of 15% in total glutathione and 20% in reduced glutathione, respectively (58, 59), and post-mortem brains ( We then investigated the correlation between behavioral improvements and changes in intracellular glutathione concentrations