glutathione s transferases Frontiers The Multifaceted Role of Glutathione

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Figure 1 Autoimmune mechanisms have also been implicated in the pathogenesis of HIVAC through HIV-induced B-cell stimulation leading to autoantibody production directed against the myocardium ( 3 Clinical manifestations and diagnosis 3.1 Signs and symptoms Like other forms of cardiomyopathy, peripheral edema, involving the legs, ankles, feet, or abdomen, frequently results from fluid retention secondary to compromised myocardial function

In addition to its role in iron metabolism, NRF2 regulates basal and inducible glutathione synthesis expression of SLC7A11 and -glutamylcysteine synthetase (-GCS) to protect against ferroptosis

See Additional file 1: Table S1 for modified reactions

Kwak, S., Jo, J

These fall into the following general categories: pyrimidines, polyenes, allylamines, azoles, echinocandins, and heterocyclic benzofurans