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Overall, these data allow the conclusion that Se levels in seminal plasma and/or serum are positively associated with good seminogram parameters, with the strongest association observed with sperm motility (as shown in 10 of 13 studies included) (171, 190, 200202, 204, 206, 208, 215)

Quantitative analysis of oxygen consumption demonstrates a 45% reduction in oxidative phosphorylation capacity, accompanied by dysregulated acyl-CoA oxidation and accumulation of oxidative stress markers, specifically 4-hydroxynonenal adducts within subcutaneous adipose deposits (87)