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Transfection of overexpressing or siRNA plasmids were carried out in 6070% confluent cells by using Lipofectamine 3000 reagent according to the manufacturers protocol

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miRNA-425 and miRNA-744 inhibited angiotensin-induced collagen and cellulose synthesis, reduced CFs activation, and improved cardiac remodeling by targeting TGF-

In addition, inhibition of cysteine desulfurase expression leads to increased intracellular reactive oxygen species levels, the promotion of ferroptosis and reduced levels of resistance to oxaliplatin (101)