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It has shown activity at very low doses (nanogram to microgram per kilogram) without demonstrable toxicity in animal studies [11]

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NNMT methylates nicotinamide to produce 1-methylnicotinamide (1-MNA), consuming SAMe and depleting cellular NAD+ pools

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While these findings suggest potent fungicidal activity, the study represents a preclinical investigation, and further validation in larger, clinically relevant models are required to establish therapeutic relevance

AOD 9604 typically has minimal side effects, but some individuals may experience mild discomfort at the injection site