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Description

B), 971977

Mice were euthanized and tissue collected immediately following the [U- 13 C]glucose infusion

Derivative of Angiotensin IV: Dihexa was designed by modifying angiotensin IV, a peptide fragment known to have cognitive effects but limited potency and stability

This necessitates either intrathecal delivery to bypass the bloodbrain barrier or systemic administration of therapies capable of crossing the bloodbrain barrier to reach the entire brain