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Since hepatic steatosis and neutrophil infiltration 1,22,23 are critical pathological features of alcohol-induced liver injury, and the previously discussed studies suggested that CBD had beneficial effect on these processes, we investigated the effects of CBD on alcohol-induced liver steatosis, metabolic changes, inflammation and neutrophil-mediated oxidative injury, using a well-established model of chronic ethanol feeding plus binge alcohol gavage (NIAAA model) 24,25 , which closely relates to human drinking behavior 26

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