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Considering that, hemoglobin concentration decreases and toxic heme is released, which usually causes hypoxia [94]

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Body fat reduction of 1 to 3 percent of total body fat over the same period is consistent with published data on GH secretagogue effects on body composition

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The decreased thiosulfate concentration seems to be associated with formation of a thiosulfate/hydroxocobalamin complex, because hydroxocobalamin can form a complex with thiosulfate

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doi: 10.1038/s41598-022-18195-8 56

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