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Two data points were omitted from analysis in vehicle group due to extensive food spillage

Spontaneous compression of both median nerves in the carpal tunnel

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Single oral doses equivalent to 4 or more mg/kg amlodipine in dogs (11 or more times the maximum recommended human dose on a mg/m2 basis) caused a marked peripheral vasodilation and hypotension

VonNoorden GK, Crawford ML (1979)