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& Zanchetti, A

The important caveats on the topical data Honesty requires naming the limitations even of the route that does have human data

PMID: 25826983

For everyone else, the copper delivered by therapeutic doses falls well within safe parameters, with 40+ years of safety data supporting this conclusion

p53 is nicknamed the guardian of the genome because it is a tumor supressor when it detects mutation in the cells DNA (which can turn the cell into cancer), it causes apoptosis (in fact, lots of cancers are associated with genetic mutations that switch off p53, meaning that p53 stops working and cant kill the cell before it forms a tumor and possibly becomes cancerous)

Piracetam: The One You Should Start With Theres a reason piracetam has been studied for sixty years and is still the first compound most serious nootropic users come back to: its the most characterised compound in the category, and starting somewhere well-understood before moving to more potent options is just good practice