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The importance of early and accurate diagnosis is becoming crucial

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Aberrant expressions of pathogenic phenotype in Alzheimer's diseased transgenic mice carrying NSE-controlled APPsw

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Some of these problems include neurological disorders, brain atrophy, demyelination, delayed cognitive development and growth, mental retardation, lack of emotional and communicative responses, lack of smiling and willingness to play, extreme fatigue, vomiting, tremors and convulsions, gait and motor coordination disorders, severe megaloblastic anemia, thrombocytopenia, pancytopenia, which can lead to coma, respiratory failure, and death