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N Engl J Med (1986) 315:4857

Frederick et al., 2016), reduces the mitochondrial unfolded protein response (Mendelsohn and Larrick, 2017), disrupts ATP biosynthesis, decreases the ability to pump calcium against the intracellular gradient (Rzheshevsky, 2014) and has deleterious effects on muscle health (Goody and Henry, 2018)

In addition to glycine, glutamate, another component of GSH, is increased in NAFLD/NASH, which has been attributed to gamma-glutamyltransferase-mediated glutamate release during GSH transamination and upregulation of hepatic glutaminase-1 (192, 203)

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If glutathione itself is new to you, our overview of what glutathione is and why levels fall with age is the place to start