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J Dermatol Sci (2015) 80:3844

490 Furthermore, Sir2 , as a mammalian homolog of SIRT1, is the downstream effector of increased Nmnat activity, which can lead to axon protection in Wallerian degeneration slow mice

The authors concluded that "those with ASDs are affected by an imbalance between their anti-oxidative and oxidative stress systems, a condition which could be treated with glutathione supplementation"

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This interindividual variability has led to the classification of three urolithin metabotypes: the UM-A strain is distinguished by its predominant production of urolithin A, while the UM-B strain produces urolithins A and B, along with their isomers

Atamer Y, Sarac S, Asik HK, Sahbaz T