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While the American Dental Association (ADA) itself has a toxic substance protocol for safe handling of the amalgam mixture once it is prepared by a dentist or assistant, the safety of dental amalgams for patients has yet to be fully addressed

Int J Pharm Pharm Sci 4(1):102106 Chanu KV, Devi LG, Srivastava SK, Kataria M, Thakuria D, Kumar S (2021) Methanolic extract of Phlogacanthus thyrsiflorus Nees leaf induces apoptosis in cancer cells

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Conversely, LicoA exhibited weaker interaction with GPX4 (Score = 7.57), xCT (Score = 6.61) and HO-1 (Score = 4.77) (Figures 4BD)

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Finally this review will highlight future directions in IBS therapy research, including identification of new molecular targets, application of 3-D gut model, gut-on-a-chip and personalized therapy