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Here we identified Lys105 of ScGrx7 and Lys26 of PfGrx as a dual activator for the catalytic cysteine residue and GSH

[DOI] [PMC free article] [PubMed] [Google Scholar] 89.Zapata J, Castro-Sepulveda M, Soto-Alarcon S, Alvarez D, Bustamante A, Villarroel G, Gallardo A, Garcia-Diaz DF, Valenzuela R, Echeverria F

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491 By regulating appetite, insulin secretion, and lipid metabolism, GLP-1RAs have potential benefits in the treatment of NAFLD, NASH, and T2DM

To overcome these limitations of GSH, pro-GSH molecules could be used to restore or increase GSH levels [25]