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N-acetylcysteine, which amongst many other effects, enhances the efficiency of mitochondrial energy generation has an efficacy signal in some but not all trials examining bipolar depression [60, 61]

Hence, autophagy serves as an important control mechanism for a range of cellular and tissue functions, such as growth, coping with stress, immune reactions, and metabolic processes

Interestingly, according to STRING analysis, associations between GSTM1 or GSTT1 with CYP2E1 or NAT2 enzymes were observed in the PPI network (Fig

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Cellular senescence is dynamic, often compromising normal tissue functionality by continuously secreting pro-inflammatory cytokines, chemokines, growth factors, and matrix metalloproteinasescollectively termed senescence-associated secretory phenotype (SASP) factors