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Further research in this field may provide valuable insights into potential therapeutic interventions for lipid-related diseases

SAMe is decisively involved in polyamine synthesis, as the production of spermidine (SPD) and spermine (SPM) from putrescine requires the sequential addition of an aminopropyl group coming from decarboxylated SAMe (dcSAMe)

In this review, we summarized the roles of several natural products, including flavonoids, polyphenols, alkaloids, terpenes, polysaccharides, coumarins, proteins and peptides, trace elements and their derivatives, Traditional Chinese Medicine, naphthoquinone compounds, steroid compounds, etc., in OC and the mechanisms by which they regulate ferroptosis-related pathways to achieve their anti-cancer effects

Increased efflux of oxidized glutathione (GSSG) causes glutathione depletion and potentially diminishes antioxidant defense in sickle erythrocytes

But it is also associated with the fact that the passage of the released enzymes through the cell wall is more efficient when the cytoplasms permeability has been increased by means of electroporation

Hopefully, there will be more clinical research about safe and efficient treatment in elderly people related to age-related diseases in the future