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The Ceribell Status Epilepticus Monitor software analyzes EEG waveforms and identifies patterns consistent with ESE as defined in the American Clinical Neurophysiology Society's Guideline 14

This approach has the advantages of expanding the druggable target space, demonstrating polypharmacology (targeting multiple targets), and identifying therapeutic agents with relatively low molecular weights

USA 109 , E3186E3195 (2012)

Although generally well-tolerated at low to moderate doses, high-dose curcumin can induce gastrointestinal discomfort, interfere with iron absorption, a concern in CKD-related anemia, and interact with drug-metabolizing enzymes [34,68]

Mirocha, H.J

2 Elevated ROS levels result in overactivation of key signaling pathways such as extracellular-regulated kinase 1/2 (ERK1/2), mitogen-activated protein kinase (MAPK), and phosphatidyl inositol 3 kinases (PI3Ks), which are crucial for regulating cell survival and propagation