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Acta Endocrinol (Copenh)

Researching Patient-Centred Delivery The current standard is a deep intramuscular (IM) injection, usually administered in a GP surgery, which consumes significant time for both the patient and the NHS

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Patients with homozygosity at this mutated locus tend to exhibit a more severe clinical phenotype, usually associated with severe mental retardation and early onset seizures, and five of them died early in life [6,7,8]

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This means that beneficiaries who have been attributed to one APM Entity and are thus barred under the terms of an Advanced APM from attribution to another APM Entity are removed from the denominator of both the payment amount method and patient count method in QP Threshold Score calculations for the APM Entity to which they cannot be attributed