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Additionally, there was a dose-dependent decrease in GSH levels in rats, indicating the production of ROS and oxidative stress

Cell Stem Cell 8 (2), 188199

Similar content being viewed by others Background Parkinsons disease (PD) is the second most common neurodegenerative disorder worldwide, affecting 23 % of the population 65 years of age (Pringsheim et al

PGI-C response of moderately improved or much improved. This group of patients, often refractory to treatment, had higher response rates with ritlecitinib than with placebo, although rates were lower than in patients without AT or AU.8 Patients with abnormal eyebrow or eyelash scores Among patients without normal eyebrow or eyelash assessment scores at baseline, improvement by 2 grades in eyebrow score or normalization of eyelash score increased over time across all four ritlecitinib groups (Fig