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ScientificWorldJournal 2014 , 818502 (2014)

One successful example is the work of the Reymond group, who have utilized this approach to discover and optimize bicyclic peptidesa class of molecules with high stability due to their constrained structure

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Understanding the molecular and cellular mechanisms underlying the loss or gain of disorder-related detrimental effects mediated by astrocytes in different contexts has the potential to identify new treatment strategies for a wide variety of CNS disorders