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An improvement in respiratory symptoms of asthma and COPD after switching was reported in 65.4% and 75.7% of the respondents, respectively

These can be broken down into three areas: Constant tiredness or low energy Red, irritated or bloodshot eyes Sudden, unexplained weight loss Shaking hands, excessive sweating Difficulty breathing or persistent coughing Anxiety, irritability or paranoia between doses Hallucinations or disturbing thoughts Emotional numbness or mood swings Memory problems or poor focus Spending large sums of money on Spice Lying about usage or becoming increasingly secretive Skipping work, school or missing important responsibilities Isolating from loved ones If several of these signs feel familiar, it might be time to step back and look honestly at the role Spice is playing in your life, or in the life of someone close to you

McCarthy A, Cancer Research UK

Dark circles caused by dehydration are often accompanied by other signs such as dry skin, headaches, fatigue, thirst, darker urine, or reduced energy levels

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