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doi: 10.1016/j.stem.2007.08.014

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Microbial Dysbiosis Modulates Protein Clearance Mechanisms, Autoimmune Functions, and Central Nervous System Immune Recruitment Aggregated misfolded protein and autophagolysosomal-proteasomal pathways participate in a vicious cycle that causes cytotoxicity and exacerbates hallmark pathologies of neurodegenerative disorders (Monaco and Fraldi, 2020)

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At high glucose levels, glycolysis is dominant and glycolytic intermediates and products are utilized to generate ATP as well as lipids and amino acids