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It promotes neutrophil chemotaxis and degranulation leading to local inflammation in damaged tissues 37

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Formulation choices vehicle, pH, penetration enhancers, concentration, and whether the peptide is stabilized against degradation can make the difference between a product that delivers an active dose and one that mostly sits on the surface

Some researchers prefer nighttime-only application, reasoning that growth hormone release during sleep may synergize with the peptide signaling

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