2037-A DIAGNOSTIC ACCURACY OF VCTE AND 2D-SWE IN BIOPSY-PROVEN NAFLD AND PERFORMANCE OF TWO-STEP APPROACHES TO PREDICT ADVANCED FIBROSIS Madalina-Gabriela Taru 1,2 , Dan-Corneliu Leucuta 2 , Lidia Neamti 2 , Anca Maniu 3 , Vlad Taru 4 , Bobe Petrushev 3 , Ioana Rusu 3 , Cristian Tefas 2,3 , Petra Fischer 2 , Andreea-Ioana Terec 5 , Lucia Maria Procopciuc 2 , Bogdan Procopet 2 , Horia Stefanescu 3 and Monica Lupsor-Platon 2,3 , (1)Department of Medical and Surgical Sciences, University of Bologna, 40126 Bologna, Italy, (2)Luliu Hatieganu University of Medicine and Pharmacy, 400012 Cluj-Napoca, Romania, (3)Octavian Fodor Regional Institute of Gastroenterology and Hepatology, 400162 Cluj-Napoca, Romania, (4)Division of Gastroenterology and Hepatology, Department of Internal Medicine III, Medical University of Vienna, (5)Niculae Stncioiu Heart Institute, 400001, Cluj-Napoca, Romania Background: Non-alcoholic fatty liver disease (NAFLD) and non-alcoholic steatohepatitis (NASH) pose significant challenges to the healthcare system, and the prediction of advanced fibrosis (F3) is a crucial aspect in their management
The reduction of c-Myc decreases the expression of GLS1, a key enzyme in Gln metabolism, resulting in impaired Gln utilization and increased sensitivity to chemotherapy in liver cancer (32)
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Fatty liver, in which fat is deposited in the liver tissue, is thought to progress to non-alcoholic steatohepatitis and liver cirrhosis (NASH) when the tissue is exposed to certain stimuli such as oxidative stress and inflammatory cytokines
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Sequestrants in food
