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Journal of Blood Medicine

[20] Patients should contact their GP or bariatric team promptly if they experience any of the following: New or worsening tingling, numbness, or weakness in the limbs Difficulty with balance, coordination, or memory Unexplained fatigue, breathlessness, or palpitations A sore or swollen tongue, or persistent mouth ulcers Any concern that they have missed supplementation for a prolonged period Symptoms that suggest anaemia, such as pallor or dizziness New or worsening neurological symptoms such as paraesthesia, gait disturbance, or cognitive change warrant same-day assessment

NAC helps sperm motility but needs to be monitored

Such studies remind us that negative or nuanced outcomes are often the most enlightening, pushing the field forward and helping refine both scientific questions and clinical practice

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