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One-way ANOVA was used to analyze statistical significance

To further understanding of the functioning of any biotransformation process, state-of-the-art modelling and optimization techniques, in combination with a study of the genome, transcriptome and proteome, as well as of the regulome, will lead to new approaches to understand these bioprocesses

Kaneko JJ, Harvey JW, Bruss ML (2008) Clinical biochemistry of domestic animals, 6th edn